The daughter of George and Rachel Stanley, Charlotte Dupuy was born in Cambridge, Maryland, in 1787. Her parents were owned and enslaved by Daniel Parker. Eight short years later, Dupuy was sold to James Condon for $100 and was forced to leave her family.
In 1805, at the age of 18, Charlotte was brought to Kentucky by Mr. Condon and was registered as his slave. While in Kentucky she met Aaron Dupuy, who was enslaved by Henry Clay and his wife, Lucretia. Charlotte and Aaron were married in 1806 and Charlotte was sold to the Clay family.
In 1825, the Clay family moved to Washington, D.C. as Henry Clay served as Secretary of State. Charlotte found a lawyer who filed papers for her and her children, suing for their freedom. Her petition was denied and Charlotte was jailed for refusing to return to Kentucky with the Clays. She was later emancipated by Henry Clay in 1840.